Research Officer/Research fellow (Colorectal cancer study) - #1160103

You will be responsible for planning and conducting experiments for a study exploring combination therapy in colorectal cancer. The responsibilities includes (but not limited to):

• Work closely with the PI and the study team to plan, execute, and troubleshoot experiments.

• Establishing, characterising, and maintaining genetically modified cancer cell models and human derived cancer organoid, including routine passaging, QC, and banking.

• Conduct cancer-immune cells co-culture and evaluate treatment responses using flow cytometry, Luminex, ELISA, immunohistochemistry (IHC), microscopy, and other related assays.

• Coordinate with collaborators on sample logistics, timelines, and data sharing.

• Maintain accurate, well-annotated experimental records and present regular updates to the PI and the study team.

• Manage laboratory operations (inventory, ordering, equipment maintenance) and ensure adherence to safety, biosafety, and institutional compliance requirements.

• Prepare progress reports for internal lab meetings, institutional reviews, and conferences.

• Contribute to manuscript preparation

• Manage daily laboratory operations, including inventory, ordering, and equipment maintenance, while ensuring adherence to institutional safety, biosafety, and compliance requirements.

Job Requirements

• Master or PhD degree in Life Sciences or a related field (or equivalent experience), with proficiency in experimental design and strong hands-on laboratory skill

• Proficient in the culture and co-culture of various mammalian cells and immune cells, with practical expertise in maintaining cell lines, handling primary cells and optimizing co-culture system to study cell-cell interactions and immune response in vitro

• Proficient in molecular techniques (e.g. flow cytometry, PCR/qPCR, cloning, transfection, Western blotting, etc.); experience in organoid culture is an advantage

• Responsible and organised; maintain clear records and follow SOPs and safety/biosafety practices.

• Collaborative; comfortable working in a team and learning new methods.